Publications: A. Marian
| Title | Year | Citations | Score |
|---|---|---|---|
|
COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options
Cardiovascular Research, 2020 View Details |
2020 | 1240 | 99.9% |
|
Hypertrophic Cardiomyopathy: Genetics, Pathogenesis, Clinical Manifestations, Diagnosis, and Therapy.
Circulation Research, 2017 View Details |
2017 | 1043 | 99.9% |
|
Evaluation of Mavacamten in Symptomatic Patients With Nonobstructive Hypertrophic Cardiomyopathy.
Journal of the American College of Cardiology, 2020 View Details |
2020 | 287 | 99.5% |
|
Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy.
Journal of Clinical Investigation, 2006 View Details |
2006 | 611 | 99.5% |
|
Identification of a genetic locus for familial atrial fibrillation.
New England Journal of Medicine, 1997 View Details |
1997 | 585 | 99.4% |
|
Tissue Doppler Imaging Consistently Detects Myocardial Abnormalities in Patients With Hypertrophic Cardiomyopathy and Provides a Novel Means for an Early Diagnosis Before and Independently of Hypertrophy
Circulation, 2001 View Details |
2001 | 604 | 99.3% |
|
Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death.
The Lancet, 1993 View Details |
1993 | 410 | 99.1% |
|
The Hippo Pathway Is Activated and Is a Causal Mechanism for Adipogenesis in Arrhythmogenic Cardiomyopathy
Circulation Research, 2014 View Details |
2014 | 253 | 99.1% |
|
A variant of human paraoxonase/arylesterase (HUMPONA) gene is a risk factor for coronary artery disease.
Journal of Clinical Investigation, 1995 View Details |
1995 | 352 | 98.7% |
|
Angiotensin II Blockade Reverses Myocardial Fibrosis in a Transgenic Mouse Model of Human Hypertrophic Cardiomyopathy
Circulation, 2001 View Details |
2001 | 387 | 98.7% |
|
Simvastatin Induces Regression of Cardiac Hypertrophy and Fibrosis and Improves Cardiac Function in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy
Circulation, 2001 View Details |
2001 | 370 | 98.6% |
|
Molecular Genetic Basis of Hypertrophic Cardiomyopathy:
Cardiovascular Electrophysiology, 1998 View Details |
1998 | 305 | 98.3% |
|
MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II.
Human Molecular Genetics, 2007 View Details |
2007 | 270 | 98.3% |
|
DNA Damage Response/TP53 Pathway Is Activated and Contributes to the Pathogenesis of Dilated Cardiomyopathy Associated With LMNA (Lamin A/C) Mutations
Circulation Research, 2019 View Details |
2019 | 125 | 98.1% |
|
The molecular genetic basis for hypertrophic cardiomyopathy.
Journal of Molecular and Cellular Cardiology, 2001 View Details |
2001 | 295 | 98.0% |
|
Molecular Genetic Basis of Hypertrophic Cardiomyopathy.
Circulation Research, 2021 View Details |
2021 | 87 | 97.9% |
|
Tissue Doppler Imaging Predicts the Development of Hypertrophic Cardiomyopathy in Subjects With Subclinical Disease
Circulation, 2003 View Details |
2003 | 275 | 97.8% |
|
Molecular genetic studies of complex phenotypes.
Translational research : the journal of laboratory and clinical medicine, 2012 View Details |
2012 | 161 | 97.6% |
|
Recent advances in the molecular genetics of hypertrophic cardiomyopathy.
Circulation, 1995 View Details |
1995 | 224 | 97.5% |
|
Nuclear Plakoglobin Is Essential for Differentiation of Cardiac Progenitor Cells to Adipocytes in Arrhythmogenic Right Ventricular Cardiomyopathy
Circulation Research, 2011 View Details |
2011 | 169 | 97.5% |
|
Angiotensin-I converting enzyme genotypes and left ventricular hypertrophy in patients with hypertrophic cardiomyopathy.
Circulation, 1995 View Details |
1995 | 217 | 97.4% |
|
Framework for development of physician competencies in genomic medicine: report of the Competencies Working Group of the Inter-Society Coordinating Committee for Physician Education in Genomics
Genetics in Medicine, 2014 View Details |
2014 | 135 | 97.4% |
|
Abstract 18430: Human Molecular Genetic and Functional Studies Identify TRIM63, Encoding Muscle RING Finger Protein 1, as a Novel Gene for Human Hypertrophic Cardiomyopathy
Circulation, 2012 View Details |
2012 | 144 | 97.2% |
|
Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism
Proceedings of the National Academy of Sciences of the United States of America, 2003 View Details |
2003 | 232 | 97.2% |
|
Myozenin 2 Is a Novel Gene for Human Hypertrophic Cardiomyopathy
Circulation Research, 2007 View Details |
2007 | 194 | 97.2% |
|
Pharmacogenetic study of statin therapy and cholesterol reduction.
Current Atherosclerosis Reports, 2005 View Details |
2005 | 211 | 97.2% |
|
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes Is Associated With Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy
Circulation Research, 2019 View Details |
2019 | 96 | 97.1% |
|
A transgenic rabbit model for human hypertrophic cardiomyopathy.
Journal of Clinical Investigation, 1999 View Details |
1999 | 204 | 96.7% |
|
Genetic Fate Mapping Identifies Second Heart Field Progenitor Cells As a Source of Adipocytes in Arrhythmogenic Right Ventricular Cardiomyopathy
Circulation Research, 2009 View Details |
2009 | 148 | 96.4% |
|
A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis.
Journal of the American College of Cardiology, 2005 View Details |
2005 | 165 | 95.9% |
|
Current state of vaccine development and targeted therapies for COVID-19: impact of basic science discoveries
Cardiovascular pathology, 2020 View Details |
2020 | 73 | 95.9% |
|
Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene.
Circulation Research, 2016 View Details |
2016 | 90 | 95.8% |
|
Tissue Doppler Imaging Consistently Detects Myocardial Contraction and Relaxation Abnormalities, Irrespective of Cardiac Hypertrophy, in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy
Circulation, 2000 View Details |
2000 | 181 | 95.8% |
|
Hypertrophic cardiomyopathy: from genetics to treatment
European Journal of Clinical Investigation, 2010 View Details |
2010 | 124 | 95.6% |
|
Transgenic Mouse Model of Ventricular Preexcitation and Atrioventricular Reentrant Tachycardia Induced by an AMP-Activated Protein Kinase Loss-of-Function Mutation Responsible for Wolff-Parkinson-White Syndrome
Circulation, 2005 View Details |
2005 | 149 | 95.3% |
|
Resolution of Established Cardiac Hypertrophy and Fibrosis and Prevention of Systolic Dysfunction in a Transgenic Rabbit Model of Human Cardiomyopathy Through Thiol-Sensitive Mechanisms
Circulation, 2009 View Details |
2009 | 124 | 95.3% |
|
Strategic approaches to unraveling genetic causes of cardiovascular diseases.
Circulation Research, 2011 View Details |
2011 | 110 | 95.2% |
|
Sudden cardiac death in hypertrophic cardiomyopathy. Variability in phenotypic expression of beta-myosin heavy chain mutations.
European Heart Journal, 1995 View Details |
1995 | 128 | 94.6% |
|
BET bromodomain inhibition attenuates cardiac phenotype in myocyte-specific Lamin A/C-deficient mice.
Journal of Clinical Investigation, 2020 View Details |
2020 | 61 | 94.6% |
|
A variant of p22(phox), involved in generation of reactive oxygen species in the vessel wall, is associated with progression of coronary atherosclerosis.
Circulation Research, 2000 View Details |
2000 | 148 | 94.5% |
|
Genetic determinants of cardiac hypertrophy
Current Opinion in Cardiology, 2008 View Details |
2008 | 115 | 94.4% |
|
Modifier genes for hypertrophic cardiomyopathy.
Current Opinion in Cardiology, 2002 View Details |
2002 | 141 | 94.2% |
|
Plasma homocyst(e)ine concentration, but not MTHFR genotype, is associated with variation in carotid plaque area.
Stroke, 1999 View Details |
1999 | 135 | 94.2% |
|
Suppression of Activated FOXO Transcription Factors in the Heart Prolongs Survival in a Mouse Model of Laminopathies
Circulation Research, 2018 View Details |
2018 | 66 | 94.2% |
|
Widespread myocardial dysfunction in COVID-19 patients detected by myocardial strain imaging using 2-D speckle-tracking echocardiography
Acta Pharmacologica Sinica, 2021 View Details |
2021 | 46 | 94.1% |
|
Antifibrotic effects of antioxidant N-acetylcysteine in a mouse model of human hypertrophic cardiomyopathy mutation.
Journal of the American College of Cardiology, 2006 View Details |
2006 | 121 | 94.0% |
|
Metabolomic distinction and insights into the pathogenesis of human primary dilated cardiomyopathy
European Journal of Clinical Investigation, 2011 View Details |
2011 | 92 | 93.8% |
|
Genetic Ablation of the DNA Damage Response Pathway Attenuates Lamin-Associated Dilated Cardiomyopathy in Mice
JACC: Basic to Translational Science, 2022 View Details |
2022 | 34 | 93.4% |
|
Clinical Interpretation and Management of Genetic Variants
JACC: Basic to Translational Science, 2020 View Details |
2020 | 52 | 93.2% |
|
Exercise Restores Dysregulated Gene Expression in a Mouse Model of Arrhythmogenic Cardiomyopathy.
Cardiovascular Research, 2019 View Details |
2019 | 53 | 92.8% |
|
Role of Candidate Modifier Genes on the Phenotypic Expression of Hypertrophy in Patients with Hypertrophic Cardiomyopathy
Journal of Investigative Medicine, 1997 View Details |
1997 | 102 | 92.2% |
|
Deletion of the Lmna gene in fibroblasts causes senescence-associated dilated cardiomyopathy by activating the double-stranded DNA damage response and induction of senescence-associated secretory phenotype
The Journal of Cardiovascular Aging, 2022 View Details |
2022 | 30 | 92.0% |
|
Single-Cell RNA Sequencing Uncovers Paracrine Functions of the Epicardial-Derived Cells in Arrhythmogenic Cardiomyopathy
Circulation, 2021 View Details |
2021 | 37 | 91.8% |
|
Novel Polymorphisms in Promoter Region of ATP Binding Cassette Transporter Gene and Plasma Lipids, Severity, Progression, and Regression of Coronary Atherosclerosis and Response to Therapy
Circulation Research, 2001 View Details |
2001 | 107 | 91.8% |
|
Elements of ‘missing heritability’
Current Opinion in Cardiology, 2012 View Details |
2012 | 69 | 91.7% |
|
Expression of a mutant (Arg92Gln) human cardiac troponin T, known to cause hypertrophic cardiomyopathy, impairs adult cardiac myocyte contractility.
Circulation Research, 1997 View Details |
1997 | 96 | 91.7% |
|
PANoptosis is a prominent feature of desmoplakin cardiomyopathy
The Journal of Cardiovascular Aging, 2022 View Details |
2022 | 29 | 91.6% |
|
Haplo-insufficiency of Tmem43 in cardiac myocytes activates the DNA damage response pathway leading to a Late-Onset Senescence-Associated pro-fibrotic cardiomyopathy.
Cardiovascular Research, 2020 View Details |
2020 | 42 | 90.9% |
|
Genetic Basis and Molecular Biology of Cardiac Arrhythmias in Cardiomyopathies.
Cardiovascular Research, 2020 View Details |
2020 | 42 | 90.9% |
|
Genome-wide mapping of modifier chromosomal loci for human hypertrophic cardiomyopathy.
Human Molecular Genetics, 2007 View Details |
2007 | 83 | 90.8% |
|
A Potential Oligogenic Etiology of Hypertrophic Cardiomyopathy: A Classic Single-Gene Disorder
Circulation Research, 2017 View Details |
2017 | 50 | 90.6% |
|
Genetics and Genomics of Single-Gene Cardiovascular Diseases: Common Hereditary Cardiomyopathies as Prototypes of Single-Gene Disorders.
Journal of the American College of Cardiology, 2016 View Details |
2016 | 49 | 90.0% |
|
Knockdown of Plakophilin 2 Downregulates miR-184 Through CpG Hypermethylation and Suppression of the E2F1 Pathway and Leads to Enhanced Adipogenesis In Vitro.
Circulation Research, 2016 View Details |
2016 | 48 | 89.8% |
|
Hypertrophy Regression With N-Acetylcysteine in Hypertrophic Cardiomyopathy (HALT-HCM): A Randomized, Placebo-Controlled, Double-Blind Pilot Study
Circulation Research, 2018 View Details |
2018 | 43 | 89.5% |
|
Molecular genetics of hypertrophic cardiomyopathy.
Annual Review of Medicine, 1996 View Details |
1996 | 72 | 88.9% |
|
Interactions between angiotensin-I converting enzyme insertion/deletion polymorphism and response of plasma lipids and coronary atherosclerosis to treatment with fluvastatin: the lipoprotein and coronary atherosclerosis study.
Journal of the American College of Cardiology, 2000 View Details |
2000 | 83 | 88.8% |
|
Cytochrome P-450 polymorphisms and response to clopidogrel
Current Atherosclerosis Reports, 2009 View Details |
2009 | 61 | 88.2% |
|
Contemporary treatment of hypertrophic cardiomyopathy.
Texas Heart Institute Journal, 2009 View Details |
2009 | 59 | 87.8% |
|
Pathogenesis of hypertrophic cardiomyopathy caused by myozenin 2 mutations is independent of calcineurin activity.
Cardiovascular Research, 2013 View Details |
2013 | 47 | 87.5% |
|
Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies.
Cardiovascular Research, 2008 View Details |
2008 | 57 | 86.8% |
|
Enhanced Transmural Fiber Rotation and Connexin 43 Heterogeneity Are Associated With an Increased Upper Limit of Vulnerability in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy
Circulation Research, 2007 View Details |
2007 | 60 | 86.7% |
|
Challenges in medical applications of whole exome/genome sequencing discoveries.
Trends in cardiovascular medicine, 2012 View Details |
2012 | 46 | 86.5% |
|
Molecular Genetic and Functional Characterization Implicate Muscle-Restricted Coiled-Coil Gene (MURC) as a Causal Gene for Familial Dilated Cardiomyopathy
Circulation: Cardiovascular Genetics, 2011 View Details |
2011 | 47 | 85.8% |
|
A prospective study of paraoxonase gene Q/R192 polymorphism and severity, progression and regression of coronary atherosclerosis, plasma lipid levels, clinical events and response to fluvastatin.
Atherosclerosis, 2001 View Details |
2001 | 64 | 85.5% |
|
Expression of a Mutation Causing Hypertrophic Cardiomyopathy Disrupts Sarcomere Assembly in Adult Feline Cardiac Myocytes
1995 View Details |
1995 | 54 | 85.3% |
|
Genetic inactivation of β-catenin is salubrious whereas its activation is deleterious in desmoplakin cardiomyopathy.
Cardiovascular Research, 2023 View Details |
2023 | 15 | 85.3% |
|
The 9p21 susceptibility locus for coronary artery disease and the severity of coronary atherosclerosis
BMC Cardiovascular Disorders, 2009 View Details |
2009 | 47 | 84.5% |
|
Meeting report - Desmosome dysfunction and disease: Alpine desmosome disease meeting.
Journal of Cell Science, 2023 View Details |
2023 | 14 | 84.0% |
|
Expression of a missense mutation in the messenger RNA for beta-myosin heavy chain in myocardial tissue in hypertrophic cardiomyopathy.
Journal of Clinical Investigation, 1992 View Details |
1992 | 45 | 84.0% |
|
The Enigma of Genetics Etiology of Atherosclerosis in the Post-GWAS Era
Current Atherosclerosis Reports, 2012 View Details |
2012 | 38 | 83.5% |
|
Nature's genetic gradients and the clinical phenotype.
Circulation: Cardiovascular Genetics, 2009 View Details |
2009 | 44 | 83.5% |
|
Causality in genetics: the gradient of genetic effects and back to Koch's postulates of causality.
Circulation Research, 2014 View Details |
2014 | 34 | 83.1% |
|
Atorvastatin and cardiac hypertrophy and function in hypertrophic cardiomyopathy: a pilot study
European Journal of Clinical Investigation, 2010 View Details |
2010 | 41 | 83.0% |
|
FAT10 protects cardiac myocytes against apoptosis.
Journal of Molecular and Cellular Cardiology, 2013 View Details |
2013 | 35 | 82.8% |
|
Release kinetics of circulating cardiac myosin binding protein-C following cardiac injury.
American Journal of Physiology. Heart and Circulatory Physiology, 2014 View Details |
2014 | 33 | 82.5% |
|
Regulatable atrial natriuretic peptide gene therapy for hypertension.
Proceedings of the National Academy of Sciences of the United States of America, 2005 View Details |
2005 | 47 | 81.9% |
|
Recent developments in cardiovascular stem cells.
Circulation Research, 2014 View Details |
2014 | 31 | 81.4% |
|
A prospective study of genetic markers of susceptibility to infection and inflammation, and the severity, progression, and regression of coronary atherosclerosis and its response to therapy
Journal of molecular medicine, 2000 View Details |
2000 | 49 | 81.2% |
|
Experimental Therapies in Hypertrophic Cardiomyopathy
Journal of Cardiovascular Translational Research, 2009 View Details |
2009 | 38 | 81.1% |
|
Cytosolic DNA sensing protein pathway is activated in human hearts with dilated cardiomyopathy
The Journal of Cardiovascular Aging, 2023 View Details |
2023 | 12 | 80.8% |
|
RNA sequencing-based transcriptome profiling of cardiac tissue implicates novel putative disease mechanisms in FLNC-associated arrhythmogenic cardiomyopathy.
International Journal of Cardiology, 2019 View Details |
2019 | 24 | 80.6% |
|
Human polymorphism of P-selectin glycoprotein ligand 1 attributable to variable numbers of tandem decameric repeats in the mucinlike region.
Blood, 2001 View Details |
2001 | 47 | 80.6% |
|
Sudden cardiac death in patients with hypertrophic cardiomyopathy: From bench to bedside with an emphasis on genetic markers
Clinical Cardiology, 1995 View Details |
1995 | 39 | 80.1% |
|
Arrhythmogenic right ventricular cardiomyopathy is a disease of cardiac stem cells
Current Opinion in Cardiology, 2010 View Details |
2010 | 33 | 79.4% |
|
Arrhythmogenic Cardiomyopathy in a Patient With a Rare Loss‐of‐Function KCNQ1 Mutation
Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2015 View Details |
2015 | 27 | 79.4% |
|
Distinct Cellular Basis for Early Cardiac Arrhythmias, the Cardinal Manifestation of Arrhythmogenic Cardiomyopathy, and the Skin Phenotype of Cardiocutaneous Syndromes
Circulation Research, 2017 View Details |
2017 | 25 | 79.2% |
|
Effects of tamoxifen inducible MerCreMer on gene expression in cardiac myocytes in mice
The Journal of Cardiovascular Aging, 2022 View Details |
2022 | 14 | 78.7% |
|
Prognostic significance of beta-myosin heavy chain mutations is reflective of their hypertrophic expressivity in patients with hypertrophic cardiomyopathy.
Journal of Investigative Medicine, 1997 View Details |
1997 | 38 | 78.6% |
|
Clinical Significance of Variants in the TTN Gene in a Large Cohort of Patients With Sporadic Dilated Cardiomyopathy
Frontiers in Cardiovascular Medicine, 2021 View Details |
2021 | 17 | 78.5% |
|
FAT10 protects against ischemia-induced ventricular arrhythmia by decreasing Nedd4-2/Nav1.5 complex formation
Cell Death and Disease, 2021 View Details |
2021 | 17 | 78.5% |
|
Modeling human disease phenotype in model organisms: "It's only a model!".
Circulation Research, 2011 View Details |
2011 | 30 | 78.3% |
|
Genomics in cardiovascular disease.
Journal of the American College of Cardiology, 2013 View Details |
2013 | 27 | 78.2% |
|
Mitochondrial genetics and human systemic hypertension.
Circulation Research, 2011 View Details |
2011 | 28 | 77.1% |
|
Knock Down of Plakophillin 2 Dysregulates Adhesion Pathway through Upregulation of miR200b and Alters the Mechanical Properties in Cardiac Cells
Cells, 2019 View Details |
2019 | 20 | 76.9% |
|
Challenges in the Diagnosis of Anderson-Fabry Disease: A Deceptively Simple and Yet Complicated Genetic Disease.
Journal of the American College of Cardiology, 2016 View Details |
2016 | 22 | 76.5% |
|
On mice, rabbits, and human heart failure.
Circulation, 2005 View Details |
2005 | 34 | 76.4% |
|
A variant of beta fibrinogen is a genetic risk factor for coronary artery disease and myocardial infarction.
Journal of Investigative Medicine, 1996 View Details |
1996 | 31 | 75.5% |
|
Molecular basis of hypertrophic and dilated cardiomyopathy.
Texas Heart Institute Journal, 1994 View Details |
1994 | 28 | 74.9% |
|
MYH 11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II
2007 View Details |
2007 | 27 | 73.3% |
|
Identification of Genes and Pathways Regulated by Lamin A in Heart
Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2020 View Details |
2020 | 16 | 73.2% |
|
Medical DNA sequencing
Current Opinion in Cardiology, 2011 View Details |
2011 | 22 | 72.5% |
|
On genetics, inflammation, and abdominal aortic aneurysm: can single nucleotide polymorphisms predict the outcome?
Circulation, 2001 View Details |
2001 | 29 | 71.9% |
|
Decreased left ventricular ejection fraction in transgenic mice expressing mutant cardiac troponin T-Q(92), responsible for human hypertrophic cardiomyopathy.
Journal of Molecular and Cellular Cardiology, 2000 View Details |
2000 | 28 | 71.2% |
|
Surprises of the genome and "personalized" medicine.
Journal of the American College of Cardiology, 2008 View Details |
2008 | 22 | 70.6% |
|
The WNT/β-catenin pathway regulates expression of the genes involved in cell cycle progression and mitochondrial oxidative phosphorylation in the postmitotic cardiac myocytes
The Journal of Cardiovascular Aging, 2022 View Details |
2022 | 10 | 70.4% |
|
The Case of "Missing Causal Genes" and the Practice of Medicine: A Sherlock Holmes Approach of Deductive Reasoning.
Circulation Research, 2016 View Details |
2016 | 15 | 68.5% |
|
ChatGPT and other artificial intelligence chatbots and biomedical writing
The Journal of Cardiovascular Aging, 2023 View Details |
2023 | 7 | 67.6% |
|
Non-syndromic cardiac progeria in a patient with the rare pathogenic p.Asp300Asn variant in the LMNA gene
BMC Medical Genetics, 2017 View Details |
2017 | 14 | 66.9% |
|
Noncoding RNAs in cardiovascular biology and disease.
Circulation Research, 2013 View Details |
2013 | 15 | 66.6% |
|
Modeling Human Disease Phenotype in Model Organisms
2011 View Details |
2011 | 15 | 65.0% |
|
PCSK9 as a Therapeutic Target in Atherosclerosis
Current Atherosclerosis Reports, 2010 View Details |
2010 | 15 | 64.8% |
|
A Calsequestrin Cis-Regulatory Motif Coupled to a Cardiac Troponin T Promoter Improves Cardiac Adeno-Associated Virus Serotype 9 Transduction Specificity
Human Gene Therapy, 2018 View Details |
2018 | 12 | 64.5% |
|
Pharmacological suppression of the WNT signaling pathway attenuates age-dependent expression of the phenotype in a mouse model of arrhythmogenic cardiomyopathy
The Journal of Cardiovascular Aging, 2021 View Details |
2021 | 9 | 63.0% |
|
A combinatorial oligogenic basis for the phenotypic plasticity between late-onset dilated and arrhythmogenic cardiomyopathy in a single family
The Journal of Cardiovascular Aging, 2021 View Details |
2021 | 9 | 63.0% |
|
On predictors of sudden cardiac death in hypertrophic cardiomyopathy.
Journal of the American College of Cardiology, 2003 View Details |
2003 | 18 | 63.0% |
|
Chromatin as the Whiteboard of Heart Disease
2015 View Details |
2015 | 12 | 62.8% |
|
Apolipoprotein ε4 is not a genetic risk factor for coronary artery disease or restenosis after percutaneous transluminal coronary angioplasty
1995 View Details |
1995 | 16 | 62.6% |
|
Congenital Heart Disease: The Remarkable Journey From the "Post-Mortem Room" to Adult Clinics.
Circulation Research, 2017 View Details |
2017 | 11 | 61.6% |
|
Determinants of plasma vitamin D levels in patients with acute coronary syndromes
European Journal of Clinical Investigation, 2011 View Details |
2011 | 12 | 60.6% |
|
Clinical and Molecular Genetic Aspects of Hypertrophic Cardiomyopathy
2005 View Details |
2005 | 14 | 59.5% |
|
A missense mutation in the β myosin heavy chain gene is a predictor of premature sudden death in patients with hypertrophic cardiomyopathy
1994 View Details |
1994 | 13 | 59.0% |
|
Identifying Modifier Loci in Existing Genome Scan Data
Annals of Human Genetics, 2008 View Details |
2008 | 12 | 58.9% |
|
Heparin-associated anti-Xa activity and platelet-derived prothrombotic and proinflammatory biomarkers in moderate to high-risk patients with acute coronary syndrome
Journal of Thrombosis and Thrombolysis, 2011 View Details |
2011 | 11 | 58.9% |
|
A Rare Loss-of-Function SCN5A Variant is Associated With Lidocaine-induced Ventricular Fibrillation
The Pharmacogenomics Journal, 2014 View Details |
2014 | 10 | 58.8% |
|
Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization
bioRxiv, 2023 View Details |
2023 | 5 | 58.3% |
|
Apolipoprotein epsilon 4 is not a genetic risk factor for coronary artery disease or restenosis after percutaneous transluminal coronary angioplasty.
American Journal of Cardiology, 1995 View Details |
1995 | 13 | 58.1% |
|
Phenotypic plasticity of sarcomeric protein mutations.
Journal of the American College of Cardiology, 2007 View Details |
2007 | 12 | 57.8% |
|
Update on hypertrophic cardiomyopathy.
Texas Heart Institute Journal, 2010 View Details |
2010 | 10 | 56.9% |
|
Recent developments in cardiovascular genetics and genomics.
Circulation Research, 2014 View Details |
2014 | 9 | 56.7% |
|
Molecular, cellular, and functional characterization of myocardial regions in hypertrophic cardiomyopathy.
Circulation Cardiovascular Imaging, 2012 View Details |
2012 | 9 | 55.8% |
|
Introduction to Cardiovascular Aging Compendium.
Circulation Research, 2018 View Details |
2018 | 8 | 55.5% |
|
Identification of established arrhythmogenic right ventricular cardiomyopathy mutation in a patient with the contrasting phenotype of hypertrophic cardiomyopathy
BMC Medical Genetics, 2017 View Details |
2017 | 8 | 54.7% |
|
Genetic Causality in Complex Traits: The Case of Uric Acid.
Journal of the American College of Cardiology, 2016 View Details |
2016 | 7 | 52.4% |
|
Clinical applications of molecular genetic discoveries.
Translational research : the journal of laboratory and clinical medicine, 2016 View Details |
2016 | 7 | 52.4% |
|
Coordinated series of studies to evaluate characteristics and mechanisms of acute coronary syndromes in high-risk patients randomly assigned to enoxaparin or unfractionated heparin: design and rationale of the SYNERGY Library.
American Heart Journal, 2004 View Details |
2004 | 10 | 52.3% |
|
Genetic Markers: Genes Involved in Atherosclerosis
Journal of Cardiovascular Risk, 1997 View Details |
1997 | 10 | 51.7% |
|
Time course of recovery of regional function following thrombolysis in acute myocardial infarction (TIMI): Preliminary observations from the TIMI trial phase II
1990 View Details |
1990 | 8 | 51.3% |
|
Circulation Research and human genetic studies.
Circulation Research, 2010 View Details |
2010 | 7 | 50.2% |
|
Efficacy of Nifekalant in Patients With Wolff‐Parkinson‐White Syndrome and Atrial Fibrillation: Electrophysiological and Clinical Findings
Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2019 View Details |
2019 | 6 | 49.8% |
|
Erratum: MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor1 and angiotensin II (Human Molecular Genetics (2007) vol. 16 (20) (2453-2462) 10.1093/hmg/ddm201)
2008 View Details |
2008 | 7 | 48.7% |
|
Copy number variants and the genetic enigma of congenital heart disease.
Circulation Research, 2014 View Details |
2014 | 6 | 48.6% |
|
On the diagnostic utility of junction plakoglobin in arrhythmogenic right ventricular cardiomyopathy.
Cardiovascular pathology, 2013 View Details |
2013 | 6 | 48.3% |
|
Genome-Wide Association Studies Complemented with Mechanistic Biological Studies Identify Sortilin 1 as a Novel Regulator of Cholesterol Trafficking
Current Atherosclerosis Reports, 2011 View Details |
2011 | 6 | 47.2% |
|
What ails the NIH peer review study sections and how to fix the review process of the grant applications
The Journal of Cardiovascular Aging, 2023 View Details |
2023 | 3 | 44.5% |
|
In vivo short-term expression of a hypertrophic cardiomyopathy mutation in adult rabbit myocardium: myofibrillar incorporation without early disarray.
Proceedings of the Association of American Physicians, 1999 View Details |
1999 | 7 | 43.9% |
|
AP19-00752 Abstract View
2019 View Details |
2019 | 4 | 41.3% |
|
Erratum: Causality in genetics: the gradient of genetic effects and back to Koch postulates of causality (American Journal of Surgical Pathology (2014) 114 (e18-e21) DOI: 10.1161/ CIRCRESAHA.114.302904)
2014 View Details |
2014 | 4 | 40.7% |
|
Cardiac Myosin Binding Protein-C Autoantibodies Are Potential Early Indicators of Cardiac Dysfunction and Patient Outcome in Acute Coronary Syndrome
JACC: Basic to Translational Science, 2017 View Details |
2017 | 4 | 40.6% |
|
Genetic basis of cardiovascular aging is at the core of human longevity
The Journal of Cardiovascular Aging, 2022 View Details |
2022 | 3 | 38.9% |
|
Can an energy-deficient heart grow bigger and stronger?
Journal of the American College of Cardiology, 2003 View Details |
2003 | 5 | 38.9% |
|
Molecular Analysis of Genotype/Phenotype Correlations of Hypertrophic Cardiomyopathy
1995 View Details |
1995 | 5 | 38.7% |
|
"Into thin air" and the genetics of complex traits.
Circulation, 2002 View Details |
2002 | 5 | 38.5% |
|
Clinical implications of the “personal” genome
Current Atherosclerosis Reports, 2008 View Details |
2008 | 4 | 38.5% |
|
Molecular Pathophysiology of Cardiomyopathies
2001 View Details |
2001 | 5 | 38.2% |
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Genetic Markers: Genes Involved in Human Hypertension
Journal of Cardiovascular Risk, 1997 View Details |
1997 | 5 | 38.2% |
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Genetic Testing in Cardiovascular Medicine.
Texas Heart Institute Journal, 2018 View Details |
2018 | 3 | 35.5% |
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A missense mutation in the beta myosin heavy chain gene is a predictor of premature sudden death in patients with hypertrophic cardiomyopathy.
Journal of Sports Medicine and Physical Fitness, 1994 View Details |
1994 | 4 | 35.1% |
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The personal genome and the practice of cardiovascular medicine.
Methodist DeBakey Cardiovascular Journal, 2010 View Details |
2010 | 3 | 34.8% |
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Molecular approaches for screening of genetic diseases.
Chest, 1995 View Details |
1995 | 4 | 34.7% |
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On genetics of dilated cardiomyopathy and transgenic models: all is not crystal clear in myopathic hearts.
Circulation Research, 2001 View Details |
2001 | 4 | 34.4% |
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Abstract 4409: Phenotypic Plasticity of LMNA Mutations in Cardiovascular System Includes Isolated Cardiac Progeria, Dilated and Hypertrophic Cardiomyopathies, Atrial Fibrillation, Conduction Defects and Degenerative Valvular Diseases
2008 View Details |
2008 | 3 | 33.5% |
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An overview of nucleic acids and gene regulation.
Herz, 1993 View Details |
1993 | 3 | 30.4% |
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Letter to the editor.
The Journal of Cardiovascular Aging, 2022 View Details |
2022 | 2 | 30.1% |
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Oligogenic Cardiomyopathy
The Journal of Cardiovascular Aging, 2021 View Details |
2021 | 2 | 28.6% |
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Cardiovascular Genetics: Focus on Genetics of Coronary Artery Disease
2015 View Details |
2015 | 2 | 28.4% |
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Long Noncoding RNAs in Cardiovascular Diseases
2015 View Details |
2015 | 2 | 28.4% |
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Severe allergies and the law - the case of anaphylaxis : ethics
2012 View Details |
2012 | 2 | 28.2% |
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DNA sequence variants and the practice of medicine
Current Opinion in Cardiology, 2010 View Details |
2010 | 2 | 28.0% |
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Phenotypic spectrum of mutations in cardiolaminopathies
2011 View Details |
2011 | 2 | 27.9% |
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Commentaries--another addition to the portfolio of Circulation Research.
Circulation Research, 2011 View Details |
2011 | 2 | 27.9% |
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The genetic basis of cardiomyopathy
2008 View Details |
2008 | 2 | 26.9% |
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Abstract 1427: Pathogenesis of Hypertrophic Cardiomyopathy Caused by the Myozenin 2 Mutations Involves Calcineurin-Dependent and -Independent Mechanisms
2008 View Details |
2008 | 2 | 26.9% |
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Genetic Predisposition to Cardiac Hypertrophy
2004 View Details |
2004 | 2 | 24.4% |
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1.P.312 Homocyst(e)ine level but not MTHFR genotype predicts carotid atherosclerosis
1997 View Details |
1997 | 2 | 23.2% |
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Errors in DNA replication and genetic diseases.
Current Opinion in Cardiology, 2013 View Details |
2013 | 1 | 18.4% |
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Mutant SRF and YAP1 remodel the chromatin to entice cardiac myocyte nuclear division
The Journal of Cardiovascular Aging, 2022 View Details |
2022 | 1 | 18.3% |
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Abstract 20201: Fibro-Adipocyte Progenitors are a Cell Source of Adipocytes in Arrhythmogenic Cardiomyopathy
2014 View Details |
2014 | 1 | 18.3% |
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The Bottleneck in Genetic Testing.
Circulation Research, 2015 View Details |
2015 | 1 | 18.3% |
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Late-breaking Basic Science Abstracts from the American Heart Association's Scientific Sessions 2012 2012 Late-breaking Basic Science Abstracts Late-breaking Basic Science Oral Session 22925 Cardiac Myosin Binding Protein C Is an Ultra-early and Cardiac-specific Biomarker of Myocardial Necrosis Repl
2012 View Details |
2012 | 1 | 18.2% |
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Abstract 21194: TRIM63, Encoding MuRF1, is a Novel Gene for Human Hypertrophic Cardiomyopathy
2010 View Details |
2010 | 1 | 18.1% |
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Role of the Extracellular Matrix in the Pathogenesis of Hypertrophic Cardiomyopathy
JACC: Basic to Translational Science, 2019 View Details |
2019 | 1 | 18.0% |
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Abstract 20536: Desmoplakin Deficient Epicardial Progenitor Cells Mediate the Development of Fibroadiposis in Arrhythmogenic Cardiomyopathy
2017 View Details |
2017 | 1 | 17.9% |
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Genome-wide association study of susceptibility alleles for coronary artery disease
Current Atherosclerosis Reports, 2008 View Details |
2008 | 1 | 17.3% |
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Clinical trials report
2007 View Details |
2007 | 1 | 16.8% |
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Cholesteryl ester transfer protein variants are associated with plasma levels of high-density lipoprotein cholesterol but not the severity or progression of coronary atherosclerosis or response to therapy
2003 View Details |
2003 | 1 | 15.5% |
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Erratum to: “Evolution of expression of cardiac phenotypes over a 4-year period in the β-myosin heavy chain-Q403 transgenic rabbit model of human hypertrophic cardiomyopathy” [J Mol Cell Cardiol 2004; 36: 663-73]
2004 View Details |
2004 | 1 | 15.5% |
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839-5 Two transgenic animal models expressing human troponin T gene mutations: One exhibiting dilated cardiomyopathy (W141) and the other exhibiting hypertrophic cardiomyopathy (Q92)
2004 View Details |
2004 | 1 | 15.5% |
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Spironolactone reverses myocyte disarray and interestitial fibrosis in the cardiac troponin T transgenic mouse model of hypertrophic cardiomyopathy
2002 View Details |
2002 | 1 | 15.1% |
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Molecular genetics of cardiomyopathies.
Herz, 1993 View Details |
1993 | 1 | 14.9% |
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Localization of the gene for familial idiopathic dilated cardiomyopathy to chromosome 1q32
1996 View Details |
1996 | 1 | 14.6% |
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MOLECULAR GENETICS OF HYPERTROPHICATHY
1995 View Details |
1995 | 1 | 14.6% |