Publications: Edward Thorp
| Title | Year | Citations | Score |
|---|---|---|---|
|
Efferocytosis fuels requirements of fatty acid oxidation and the electron transport chain to polarize macrophages for tissue repair
Cell metabolism 29 (2), 443-456. e5, 2019 View Details |
2019 | 256 | 95.5% |
|
Therapeutic inflammatory monocyte modulation using immune-modifying microparticles
Science translational medicine 6 (219), 219ra7-219ra7, 2014 View Details |
2014 | 363 | 94.6% |
|
Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe−/− and Ldlr−/− mice lacking CHOP
Cell metabolism 9 (5), 474-481, 2009 View Details |
2009 | 393 | 93.0% |
|
Cytomegalovirus latency and reactivation: an intricate interplay with the host immune response
Frontiers in cellular and infection microbiology 10, 130, 2020 View Details |
2020 | 151 | 93.0% |
|
Enhanced efferocytosis of apoptotic cardiomyocytes through myeloid-epithelial-reproductive tyrosine kinase links acute inflammation resolution to cardiac repair after infarction
Circulation research 113 (8), 1004-1012, 2013 View Details |
2013 | 300 | 92.5% |
|
Mertk receptor mutation reduces efferocytosis efficiency and promotes apoptotic cell accumulation and plaque necrosis in atherosclerotic lesions of apoe−/− mice
Arteriosclerosis, thrombosis, and vascular biology 28 (8), 1421-1428, 2008 View Details |
2008 | 372 | 92.3% |
|
Macrophage-produced VEGFC is induced by efferocytosis to ameliorate cardiac injury and inflammation
The Journal of Clinical Investigation 132 (9), 2022 View Details |
2022 | 60 | 92.3% |
|
MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis
The Journal of clinical investigation 127 (2), 564-568, 2017 View Details |
2017 | 179 | 90.1% |
|
Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK)
Journal of Biological Chemistry 286 (38), 33335-33344, 2011 View Details |
2011 | 264 | 89.9% |
|
Lymphoangiocrine signals promote cardiac growth and repair
Nature 588 (7839), 705-711, 2020 View Details |
2020 | 105 | 89.5% |
|
Mechanisms and consequences of efferocytosis in advanced atherosclerosis
Journal of leukocyte biology 86 (5), 1089-1095, 2009 View Details |
2009 | 257 | 88.6% |
|
MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation
Proceedings of the National Academy of Sciences 113 (23), 6526-6531, 2016 View Details |
2016 | 168 | 88.5% |
|
MerTK cleavage on resident cardiac macrophages compromises repair after myocardial ischemia reperfusion injury
Circulation research 121 (8), 930-940, 2017 View Details |
2017 | 155 | 88.4% |
|
Toll‐like receptor‐mediated IRE1α activation as a therapeutic target for inflammatory arthritis
The EMBO journal 32 (18), 2477-2490, 2013 View Details |
2013 | 204 | 88.2% |
|
Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs
The Journal of clinical investigation 123 (1), 179-188, 2013 View Details |
2013 | 193 | 87.4% |
|
Guidelines for in vivo mouse models of myocardial infarction
American Journal of Physiology-Heart and Circulatory Physiology, 2021 View Details |
2021 | 62 | 87.0% |
|
ABCA1 and ABCG1 protect against oxidative stress–induced macrophage apoptosis during efferocytosis
Circulation research 106 (12), 1861-1869, 2010 View Details |
2010 | 212 | 86.0% |
|
Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice
The Journal of clinical investigation 122 (4), 2012 View Details |
2012 | 178 | 85.4% |
|
Wireless, implantable catheter-type oximeter designed for cardiac oxygen saturation
Science Advances 7 (7), eabe0579, 2021 View Details |
2021 | 50 | 83.6% |
|
Macrophage AXL receptor tyrosine kinase inflames the heart after reperfused myocardial infarction
The Journal of clinical investigation 131 (6), 2021 View Details |
2021 | 50 | 83.6% |
|
Intercellular adhesion molecule 1 functions as an efferocytosis receptor in inflammatory macrophages
The American journal of pathology 190 (4), 874-885, 2020 View Details |
2020 | 69 | 83.4% |
|
Tailoring nanostructure morphology for enhanced targeting of dendritic cells in atherosclerosis
ACS nano 10 (12), 11290-11303, 2016 View Details |
2016 | 112 | 82.3% |
|
Lysosomal cholesterol hydrolysis couples efferocytosis to anti-inflammatory oxysterol production
Circulation research 122 (10), 1369-1384, 2018 View Details |
2018 | 93 | 82.2% |
|
Immunometabolic mechanisms of heart failure with preserved ejection fraction
Nature cardiovascular research 1 (3), 211-222, 2022 View Details |
2022 | 28 | 81.8% |
|
Disruption of Glut1 in Hematopoietic Stem Cells Prevents Myelopoiesis and Enhanced Glucose Flux in Atheromatous Plaques of ApoE−/− Mice
Circulation research 118 (7), 1062-1077, 2016 View Details |
2016 | 108 | 81.7% |
|
Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet
Circulation research 105 (11), 1072-1082, 2009 View Details |
2009 | 161 | 81.5% |
|
Macrophages in heart failure with reduced versus preserved ejection fraction
Trends in molecular medicine 25 (4), 328-340, 2019 View Details |
2019 | 66 | 79.4% |
|
An AXL/LRP-1/RANBP9 complex mediates DC efferocytosis and antigen cross-presentation in vivo
The Journal of clinical investigation 124 (3), 1296-1308, 2014 View Details |
2014 | 111 | 79.3% |
|
The role of macrophages and dendritic cells in the clearance of apoptotic cells in advanced atherosclerosis
European journal of immunology 41 (9), 2515-2518, 2011 View Details |
2011 | 132 | 79.2% |
|
Identification of a non-growth factor role for GM-CSF in advanced atherosclerosis: promotion of macrophage apoptosis and plaque necrosis through IL-23 signaling
Circulation research 116 (2), e13-e24, 2015 View Details |
2015 | 97 | 77.9% |
|
Surface engineered polymersomes for enhanced modulation of dendritic cells during cardiovascular immunotherapy
Advanced functional materials 29 (42), 1904399, 2019 View Details |
2019 | 60 | 77.4% |
|
Single-cell RNA sequencing uncovers heterogenous transcriptional signatures in macrophages during efferocytosis
Scientific reports 10 (1), 14333, 2020 View Details |
2020 | 49 | 76.7% |
|
Brief Report: Increased Apoptosis in Advanced Atherosclerotic Lesions of Apoe−/− Mice Lacking Macrophage Bcl-2
Arteriosclerosis, thrombosis, and vascular biology 29 (2), 169-172, 2009 View Details |
2009 | 124 | 76.5% |
|
Requirements for CEACAMs and cholesterol during murine coronavirus cell entry
Journal of virology 78 (6), 2682-2692, 2004 View Details |
2004 | 141 | 76.2% |
|
Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylation
Nature metabolism 3 (10), 1313-1326, 2021 View Details |
2021 | 34 | 75.8% |
|
Mechanism of enhanced MerTK-dependent macrophage efferocytosis by extracellular vesicles
Arteriosclerosis, thrombosis, and vascular biology 39 (10), 2082-2096, 2019 View Details |
2019 | 55 | 75.4% |
|
Cholesterol-induced apoptotic macrophages elicit an inflammatory response in phagocytes, which is partially attenuated by the Mer receptor
Journal of Biological Chemistry 281 (10), 6707-6717, 2006 View Details |
2006 | 117 | 74.0% |
|
Myeloid receptor CD36 is required for early phagocytosis of myocardial infarcts and induction of Nr4a1-dependent mechanisms of cardiac repair
The FASEB Journal 32 (1), 254, 2018 View Details |
2018 | 58 | 72.5% |
|
Hypoxia-inducible factors individually facilitate inflammatory myeloid metabolism and inefficient cardiac repair
Journal of Experimental Medicine 218 (9), e20200667, 2021 View Details |
2021 | 29 | 72.0% |
|
Palmitoylations on murine coronavirus spike proteins are essential for virion assembly and infectivity
Journal of virology 80 (3), 1280-1289, 2006 View Details |
2006 | 104 | 71.7% |
|
Diet-induced obesity causes long QT and reduces transcription of voltage-gated potassium channels
Journal of molecular and cellular cardiology 59, 151-158, 2013 View Details |
2013 | 79 | 70.5% |
|
Mechanisms of failed apoptotic cell clearance by phagocyte subsets in cardiovascular disease
Apoptosis 15, 1124-1136, 2010 View Details |
2010 | 81 | 67.5% |
|
Deposition of microparticles by neutrophils onto inflamed epithelium: a new mechanism to disrupt epithelial intercellular adhesions and promote transepithelial migration
The FASEB journal 30 (12), 4007, 2016 View Details |
2016 | 56 | 66.8% |
|
Pivotal advance: macrophages become resistant to cholesterol-induced death after phagocytosis of apoptotic cells
Journal of Leucocyte Biology 82 (5), 1040-1050, 2007 View Details |
2007 | 79 | 65.8% |
|
Nanoparticle platforms for antigen-specific immune tolerance
Frontiers in immunology 11, 945, 2020 View Details |
2020 | 31 | 65.5% |
|
Single cell transcriptomics of mouse kidney transplants reveals a myeloid cell pathway for transplant rejection
JCI insight 5 (20), 2020 View Details |
2020 | 30 | 64.6% |
|
The kinetics of circulating monocyte subsets and monocyte-platelet aggregates in the acute phase of ST-elevation myocardial infarction: associations with 2-year cardiovascular events
Medicine 95 (18), 2016 View Details |
2016 | 50 | 63.8% |
|
Constitutive expression of a dominant-negative TGF-β type II receptor in the posterior left atrium leads to beneficial remodeling of atrial fibrillation substrate
Circulation research 119 (1), 69-82, 2016 View Details |
2016 | 49 | 63.3% |
|
Immunometabolism of phagocytes and relationships to cardiac repair
Frontiers in Cardiovascular Medicine 6, 42, 2019 View Details |
2019 | 34 | 63.1% |
|
Immunometabolism at the Heart of Cardiovascular Disease
JACC: Basic to Translational Science, 2023 View Details |
2023 | 7 | 61.8% |
|
Acute CD47 blockade during ischemic myocardial reperfusion enhances phagocytosis-associated cardiac repair
Basic to Translational Science 2 (4), 386-397, 2017 View Details |
2017 | 41 | 60.6% |
|
A clinically relevant murine model unmasks a “two-hit” mechanism for reactivation and dissemination of cytomegalovirus after kidney transplant
American Journal of Transplantation 19 (9), 2421-2433, 2019 View Details |
2019 | 30 | 59.6% |
|
Pioglitazone increases macrophage apoptosis and plaque necrosis in advanced atherosclerotic lesions of nondiabetic low-density lipoprotein receptor–null mice
Circulation 116 (19), 2182-2190, 2007 View Details |
2007 | 60 | 59.5% |
|
Dietary saturated fat promotes arrhythmia by activating NOX2 (NADPH Oxidase 2)
Circulation: Arrhythmia and Electrophysiology 12 (11), e007573, 2019 View Details |
2019 | 28 | 57.6% |
|
Single-cell profiling reveals inflammatory polarization of human carotid versus femoral plaque leukocytes
JCI insight 8 (17), 2023 View Details |
2023 | 6 | 57.1% |
|
Endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 controls B-cell immunity through degradation of the death receptor CD95/Fas
Proceedings of the National Academy of Sciences 113 (37), 10394-10399, 2016 View Details |
2016 | 38 | 56.3% |
|
T-cell exhaustion in allograft rejection and tolerance
Current opinion in organ transplantation 20 (1), 37, 2015 View Details |
2015 | 40 | 55.6% |
|
Genome-wide differential expression profiling of lncRNAs and mRNAs associated with early diabetic cardiomyopathy
Scientific reports 9 (1), 15345, 2019 View Details |
2019 | 26 | 55.6% |
|
Receptor tyrosine kinase MerTK suppresses an allogenic type I IFN response to promote transplant tolerance
American Journal of Transplantation 19 (3), 674-685, 2019 View Details |
2019 | 25 | 54.4% |
|
The endoplasmic reticulum–resident E3 ubiquitin ligase Hrd1 controls a critical checkpoint in B cell development in mice
Journal of Biological Chemistry 293 (33), 12934-12944, 2018 View Details |
2018 | 29 | 54.3% |
|
Monocytes prime autoreactive T cells after myocardial infarction
American Journal of Physiology-Heart and Circulatory Physiology 318 (1 …, 2020 View Details |
2020 | 20 | 53.4% |
|
Cardiomyocyte-specific ablation of Med1 subunit of the mediator complex causes lethal dilated cardiomyopathy in mice
PloS one 11 (8), e0160755, 2016 View Details |
2016 | 34 | 53.3% |
|
ACAT inhibition reduces the progression of preexisting, advanced atherosclerotic mouse lesions without plaque or systemic toxicity
Arteriosclerosis, thrombosis, and vascular biology 33 (1), 4-12, 2013 View Details |
2013 | 39 | 52.8% |
|
Macrophage-endothelial cell crosstalk orchestrates neutrophil recruitment in inflamed mucosa
The Journal of Clinical Investigation, 2023 View Details |
2023 | 5 | 51.6% |
|
Cardiac macrophages and emerging roles for their metabolism after myocardial infarction
Journal of Clinical Investigation 133 (18), e171953, 2023 View Details |
2023 | 5 | 51.6% |
|
Efferocytosis and outside-in signaling by cardiac phagocytes. Links to repair, cellular programming, and intercellular crosstalk in heart
Frontiers in immunology 8, 1428, 2017 View Details |
2017 | 27 | 49.5% |
|
Extracellular signal-regulated kinase activation during cardiac hypertrophy reduces sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) transcription
Journal of molecular and cellular cardiology 75, 58-63, 2014 View Details |
2014 | 32 | 48.7% |
|
HIF-2α in resting macrophages tempers mitochondrial reactive oxygen species to selectively repress MARCO-dependent phagocytosis
The Journal of Immunology 197 (9), 3639-3649, 2016 View Details |
2016 | 28 | 48.1% |
|
Contrasting inflammation resolution during atherosclerosis and post myocardial infarction at the level of monocyte/macrophage phagocytic clearance
Frontiers in immunology 3, 39, 2012 View Details |
2012 | 33 | 47.7% |
|
Cardiomyocytes induce macrophage receptor shedding to suppress phagocytosis
Journal of molecular and cellular cardiology 87, 171-179, 2015 View Details |
2015 | 29 | 47.4% |
|
Shedding of TNF receptor 2 by effector CD8+ T cells by ADAM17 is important for regulating TNF-α availability during influenza infection
Journal of Leucocyte Biology 98 (3), 423-434, 2015 View Details |
2015 | 28 | 46.6% |
|
Depletion of regulatory T cells decreases cardiac parasitosis and inflammation in experimental Chagas disease
Parasitology research 114, 1167-1178, 2015 View Details |
2015 | 27 | 45.7% |
|
Quantitation of acute necrosis after experimental myocardial infarction
Necrosis: Methods and Protocols, 115-133, 2013 View Details |
2013 | 28 | 44.7% |
|
New insights into the molecular mechanisms and immune control of cytomegalovirus reactivation
Transplantation 104 (5), e118, 2020 View Details |
2020 | 14 | 43.3% |
|
Protein tyrosine phosphatase 1B negatively regulates S100A9-mediated lung damage during respiratory syncytial virus exacerbations
Mucosal immunology 9 (5), 1317-1329, 2016 View Details |
2016 | 23 | 43.2% |
|
Differential role of B cells and IL-17 versus IFN-γ during early and late rejection of pig islet xenografts in mice
Transplantation 101 (8), 1801, 2017 View Details |
2017 | 21 | 43.1% |
|
A reporter for tracking the UPR in vivo reveals patterns of temporal and cellular stress during atherosclerotic progression
Journal of lipid research 52 (5), 1033-1038, 2011 View Details |
2011 | 26 | 42.4% |
|
Identification and analysis of circulating long non-coding RNAs with high significance in diabetic cardiomyopathy
Scientific reports 11 (1), 2571, 2021 View Details |
2021 | 10 | 41.3% |
|
Kidney-intrinsic factors determine the severity of ischemia/reperfusion injury in a mouse model of delayed graft function
Kidney international 98 (6), 1489-1501, 2020 View Details |
2020 | 13 | 41.3% |
|
Shedding light on impaired efferocytosis and nonresolving inflammation
Circulation research 113 (1), 9-12, 2013 View Details |
2013 | 23 | 40.5% |
|
Functional implications of neutrophil metabolism during ischemic tissue repair
Current Opinion in Pharmacology 63, 102191, 2022 View Details |
2022 | 6 | 39.9% |
|
Resolving inflammatory links between myocardial infarction and vascular dementia
Seminars in immunology 59, 101600, 2022 View Details |
2022 | 6 | 39.9% |
|
The myocardial unfolded protein response during ischemic cardiovascular disease
Biochemistry research international 2012, 2012 View Details |
2012 | 21 | 37.9% |
|
Macrophage metabolic signaling during ischemic injury and cardiac repair
Immunometabolism 3 (2), e210018, 2021 View Details |
2021 | 8 | 35.1% |
|
Phagocyte–myocyte interactions and consequences during hypoxic wound healing
Cellular immunology 291 (1-2), 65-73, 2014 View Details |
2014 | 16 | 33.7% |
|
Innate functions of dendritic cell subsets in cardiac allograft tolerance
Frontiers in immunology 11, 869, 2020 View Details |
2020 | 9 | 32.0% |
|
Can polarization of macrophage metabolism enhance cardiac regeneration?
Journal of molecular and cellular cardiology 160, 87-96, 2021 View Details |
2021 | 7 | 31.6% |
|
Allograft inflammatory factor-1 links T-cell activation, interferon response, and macrophage activation in chronic Kawasaki disease arteritis
Journal of the Pediatric Infectious Diseases Society 6 (3), e94-e102, 2017 View Details |
2017 | 12 | 30.8% |
|
PIMT/NCOA6IP deletion in the mouse heart causes delayed cardiomyopathy attributable to perturbation in energy metabolism
International journal of molecular sciences 19 (5), 1485, 2018 View Details |
2018 | 11 | 30.6% |
|
Murine cytomegalovirus dissemination but not reactivation in donor-positive/recipient-negative allogeneic kidney transplantation can be effectively prevented by transplant immune tolerance
Kidney international 98 (1), 147-158, 2020 View Details |
2020 | 8 | 29.5% |
|
Enhanced efferocytosis of apoptotic cardiomyocytes through MER tyrosine kinase links acute inflammation resolution to cardiac repair after infarction
Circulation research 113 (8), 2013 View Details |
2013 | 12 | 28.5% |
|
Monocyte subsets, T cell activation profiles, and stroke in men and women: The Multi-Ethnic Study of Atherosclerosis and Cardiovascular Health Study
Atherosclerosis 351, 18-25, 2022 View Details |
2022 | 4 | 28.3% |
|
Long-term trajectories of left ventricular ejection fraction in patients with chronic inflammatory diseases and heart failure: an analysis of electronic health records
Circulation: Heart Failure 14 (8), e008478, 2021 View Details |
2021 | 6 | 27.9% |
|
Cardiopulmonary Bypass–Induced Inflammation and Myocardial Ischemia and Reperfusion Injury Stimulates Accumulation of Soluble MER
Pediatric Critical Care Medicine 22 (9), 822-831, 2021 View Details |
2021 | 6 | 27.9% |
|
Bone marrow-derived AXL tyrosine kinase promotes mitogenic crosstalk and cardiac allograft vasculopathy
The Journal of Heart and Lung Transplantation 40 (6), 435-446, 2021 View Details |
2021 | 5 | 23.8% |
|
Comparative risk of incident coronary heart disease across chronic inflammatory diseases
Frontiers in Cardiovascular Medicine 8, 757738, 2021 View Details |
2021 | 5 | 23.8% |
|
Mitochondrial indigestion after lipid scavenging
Circulation research 125 (12), 1103-1105, 2019 View Details |
2019 | 6 | 22.0% |
|
MCMV dissemination from latently-infected allografts following transplantation into pre-tolerized recipients
Pathogens 9 (8), 607, 2020 View Details |
2020 | 5 | 20.1% |
|
Methods and models for monitoring UPR-associated macrophage death during advanced atherosclerosis
Methods in enzymology 489, 277-296, 2011 View Details |
2011 | 6 | 19.5% |
|
Proresolving lipid mediators restore balance to the vulnerable plaque
Circulation research 119 (9), 972-974, 2016 View Details |
2016 | 6 | 18.8% |
|
Acute and chronic phagocyte determinants of cardiac allograft vasculopathy
Seminars in immunopathology 40, 593-603, 2018 View Details |
2018 | 5 | 17.8% |
|
Doxorubicin-induced Ascension of resident cardiac macrophages
Circulation research 127 (5), 628-630, 2020 View Details |
2020 | 4 | 16.6% |
|
Acute murine cytomegalovirus disrupts established transplantation tolerance and causes recipient allo-sensitization
American Journal of Transplantation 21 (2), 515-524, 2021 View Details |
2021 | 3 | 14.3% |
|
Cardio-omentopexy reduces cardiac fibrosis and heart failure after experimental pressure overload
The Annals of thoracic surgery 107 (5), 1448-1455, 2019 View Details |
2019 | 3 | 12.2% |
|
Lysosomal cholesterol hydrolysis couples efferocytosis to anti-inflammatory oxysterol production
Atherosclerosis 287, e77, 2019 View Details |
2019 | 2 | 7.3% |
|
Diversity of coronavirus spikes: relationship to pathogen entry and dissemination
Viral Membrane Proteins: Structure, Function, and Drug Design, 49-63, 2005 View Details |
2005 | 2 | 7.0% |
|
Differential effects of pioglitazone on advanced atherosclerotic lesions
The American journal of pathology 175 (3), 1348, 2009 View Details |
2009 | 2 | 6.8% |
|
Histopathologic and Mechanistic Studies Related to MerTK Cleavage, a Possible Mechanism for Defective Apoptotic Cell Clearance and Plaque Necrosis in Advanced Atheromata
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 30 (11), E186-E187, 2010 View Details |
2010 | 2 | 6.6% |
|
Pioglitazone increases macrophage apoptosis and plaque necrosis in advanced atherosclerotic lesions of LDL receptor-deficient mice
Arteriosclerosis thrombosis and vascular biology 27 (6), E62-E62, 2007 View Details |
2007 | 2 | 6.6% |
|
Correction: Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice
Plos one 11 (9), e0164316, 2016 View Details |
2016 | 2 | 6.4% |
|
basic science
View Details |
2012 | 2 | 6.3% |
|
Select macrophage noncoding RNAs of interest in cardiovascular disease
Journal of Lipid and Atherosclerosis 9 (1), 153-161, 2020 View Details |
2020 | 1 | 0.0% |
|
MERTK Mediates Transplantation Tolerance via Inhibition of TBK1 Phosphorylation and IFN-a Production.
AMERICAN JOURNAL OF TRANSPLANTATION 17, 710-710, 2017 View Details |
2017 | 1 | 0.0% |